Search results for " survival"

showing 10 items of 1946 documents

Role of Bacillus thuringiensis Cry1A toxins domains in the binding to the ABCC2 receptor from Spodoptera exigua

2018

Abstract Cry proteins from Bacillus thuringiensis (Bt) have been used to control insect pests either as formulated sprays or as in Bt-crops. However, field-evolved resistance to Bt proteins is threatening the long-term use of Bt products. The SeABCC2 locus has been genetically linked to resistance to a Bt bioinsecticide (Xentari™) in Spodoptera exigua (a mutation producing a truncated form of the transporter lacking an ATP binding domain was found in the resistant insects). Here, we investigated the role of SeABCC2 in the mode of action of Cry1Aa, Cry1Ab, Cry1Ac, Cry1Ca, and two Cry1A-1Ca hybrids by expressing the receptor in Sf21 and HEK293T cell lines. Cell toxicity assays showed that Sf2…

0106 biological sciences0301 basic medicineCell SurvivalBacillus thuringiensisGene ExpressionSpodopteraSpodopteraTransfection01 natural sciencesBiochemistryHemolysin ProteinsStructure-Activity Relationship03 medical and health sciencesBacterial ProteinsProtein DomainsBacillus thuringiensisExiguaSf9 CellsAnimalsHumansProtein IsoformsBinding siteReceptorMolecular BiologySf21Binding SitesBacillus thuringiensis Toxinsbiologyfungibiology.organism_classificationMultidrug Resistance-Associated Protein 2Recombinant ProteinsClone CellsEndotoxins010602 entomologyHEK293 Cells030104 developmental biologyBiochemistryCry1AcLarvaInsect ScienceMutationInsect ProteinsMultidrug Resistance-Associated ProteinsPlasmidsProtein BindingBinding domainInsect Biochemistry and Molecular Biology
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Coping with the climate: cuticular hydrocarbon acclimation of ants under constant and fluctuating conditions

2018

International audience; Terrestrial arthropods achieve waterproofing by a layer of cuticular hydrocarbons (CHCs). At the same time, CHCs also serve as communication signals. To maintain waterproofing under different climate conditions, insects adjust the chemical composition of their CHC layer, but this may affect the communication via CHCs. The detailed acclimatory changes of CHCs and how these influence their physical properties are still unknown. Here, we studied acclimation in two closely related ant species with distinct CHC profiles, Myrmica rubra and Myrmica ruginodis, in response to constant or fluctuating temperature and humidity regimes. We measured how acclimation affected CHC co…

0106 biological sciences0301 basic medicineHot TemperaturePhysiologyDesiccation resistanceAcclimatizationClimateClimate Change[PHYS.PHYS.PHYS-BIO-PH]Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph]Phenotypic plasticityAquatic ScienceMyrmica rubra010603 evolutionary biology01 natural sciencesAcclimatizationDrought survivalCHCs03 medical and health sciencesSpecies SpecificityAnimalsRelative humidityMyrmica ruginodisSolid contentMicrorheologyMolecular BiologyEcology Evolution Behavior and Systematicschemistry.chemical_classificationPhenotypic plasticitybiologyAntsEcologyViscosityHumidityHumidity15. Life on landbiology.organism_classificationHydrocarbons[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology030104 developmental biologyHydrocarbonchemistry13. Climate actionInsect ScienceAnimal Science and Zoology[SDV.EE.BIO]Life Sciences [q-bio]/Ecology environment/BioclimatologyRheology[PHYS.COND.CM-SCM]Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft]
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Benefits of immune protection versus immunopathology costs: a synthesis from cytokine KO models.

2017

5 pages; International audience; The inflammatory response can produce damage to host tissues and in several infectious diseases the most severe symptoms are due to immunopathology rather than a direct effect of pathogen multiplication. One hypothesis for the persistence of inflammatory damage posits that the benefits of protection towards infection outweigh the costs. We used data on knocked-out (KO) cytokine models [and the corresponding wild-type (WT) controls] to test this hypothesis. We computed differences in pathogen load and host survival between WT and KO and divided them by the WT values. Using this ratio provides an internal control for variation in pathogen species, host strain,…

0106 biological sciences0301 basic medicineMicrobiology (medical)medicine.medical_treatmentVirulenceInflammationImmunopathologyBiologyCommunicable Diseases010603 evolutionary biology01 natural sciencesMicrobiologyPersistence (computer science)Gene Knockout Techniques03 medical and health sciencesImmunopathologyGeneticsmedicine[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisAnimalsHumans[ SDV.IMM ] Life Sciences [q-bio]/ImmunologyMolecular BiologyPathogenCytokineEcology Evolution Behavior and SystematicsInflammationVirulenceHost (biology)Immune protectionHost survivalComputational BiologyPathogen loadDisease Models Animal030104 developmental biologyInfectious DiseasesCytokineHost-Pathogen InteractionsImmunologyCytokinesmedicine.symptom
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Oxygen Availability during Growth Modulates the Phytochemical Profile and the Chemo-Protective Properties of Spinach Juice.

2018

Fruits and vegetables are a good source of potentially biologically active compounds. Their regular consumption in the human diet can help reduce the risk of developing chronic diseases such as cardiovascular diseases and cancer. Plants produce additional chemical substances when subject to abiotic stress or infected by microorganisms. The phytochemical profile of spinach leaves (Spinacia oleracea L.), which is a vegetable with widely recognized health-promoting activity, has been affected by applying root hypoxic and re-oxygenation stress during plant growth. Leaf juice at different sampling times has been subject to liquid chromatography mass spectrometry (LC-MSn) analysis and tested on t…

0106 biological sciences0301 basic medicineSpinaciaAntioxidantHT29 cell lineCell Survivalmedicine.medical_treatmentLiquid Chromatography-Mass Spectrometry<i>Spinacia oleracea</i> L.lcsh:QR1-502antioxidant activitySpinacia oleracea L.Anti-proliferative activity; Antioxidant activity; Comet Assay; HT29 cell line; Liquid Chromatography-Mass Spectrometry; Spinacia oleracea L;medicine.disease_cause01 natural sciencesBiochemistrylcsh:MicrobiologyAntioxidantsMass SpectrometryArticle03 medical and health sciencesSpinacia oleraceamedicineHumansFood scienceMolecular BiologyCell ProliferationbiologyAbiotic stressChemistryChemistry PhysicalPlant Extractsfood and beveragesBiological activitybiology.organism_classificationAntineoplastic Agents PhytogenicComet assayFruit and Vegetable JuicesOxygen030104 developmental biologyPhytochemicalSpinachanti-proliferative activityComet AssayDrug Screening Assays AntitumorHT29 CellsOxidative stress010606 plant biology & botanyChromatography LiquidBiomolecules
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Evaluating structural and compositional canopy characteristics to predict the light-demand signature of the forest understorey in mixed, semi-natural…

2020

Questions: Light availability at the forest floor affects many forest ecosystem processes, and is often quantified indirectly through easy-to-measure stand characteristics. We investigated how three such characteristics, basal area, canopy cover and canopy closure, were related to each other in structurally complex mixed forests. We also asked how well they can predict the light-demand signature of the forest understorey (estimated as the mean Ellenberg indicator value for light [“EIVLIGHT”] and the proportion of “forest specialists” [“%FS”] within the plots). Furthermore, we asked whether accounting for the shade-casting ability of individual canopy species could improve predictions of EIV…

0106 biological sciencesCanopy[SDV]Life Sciences [q-bio]DIVERSITYAtmospheric sciences01 natural sciencescanopy closureshade-casting abilityBasal areaSOLAR-RADIATION TRANSMITTANCEherb layerlight availabilityEnvironmental planningEcologyPolicy and LawTemperate forestForestryVegetationUnderstoryPE&RCCOMMUNITYbasal areaEcosystems Researchlight transmittanceLife Sciences & BiomedicineTemperate rainforestMonitoringEnvironmental Sciences & EcologyManagement Monitoring Policy and Law010603 evolutionary biologyEcology and EnvironmentEllenberg indicator valuesunderstoreyForest ecologyGAP FORMATIONMANAGEMENTBosecologie en Bosbeheer/dk/atira/pure/core/keywords/biologyNature and Landscape ConservationForest floorScience & Technology/dk/atira/pure/core/keywords/557265479Plant SciencesSEEDLING SURVIVAL15. Life on landCOVERForest Ecology and Forest ManagementLAYEREarth and Environmental Sciencestemperate forestcanopy coverEnvironmental scienceVEGETATION010606 plant biology & botanyRESPONSESApplied Vegetation Science
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The Spodoptera exigua ABCC2 Acts as a Cry1A Receptor Independently of its Nucleotide Binding Domain II

2019

ABC proteins are primary-active transporters that require the binding and hydrolysis of ATP to transport substrates across the membrane. Since the first report of an ABCC2 transporter as receptor of Cry1A toxins, the number of ABC transporters known to be involved in the mode of action of Cry toxins has increased. In Spodoptera exigua, a mutation in the SeABCC2 gene is described as genetically linked to resistance to the Bt-product XentariTM. This mutation affects an intracellular domain involved in ATP binding, but not the extracellular loops. We analyzed whether this mutation affects the role of the SeABCC2 as a functional receptor to Cry1A toxins. The results show that Sf21 cells express…

0106 biological sciencesCell SurvivalHealth Toxicology and Mutagenesislcsh:MedicineReceptors Cell SurfaceATP-binding cassette transporterSpodopteraSpodopteraToxicologymedicine.disease_causeBt resistance01 natural sciencesArticleCell LineHemolysin Proteins03 medical and health sciencesBacterial Proteinsmode of actionGTP-Binding ProteinsATP hydrolysismedicineAnimalsReceptor030304 developmental biology0303 health sciencesMutationBacillus thuringiensis ToxinsbiologyChemistryfungilcsh:Rheterologous expressionTransporterbiology.organism_classificationMultidrug Resistance-Associated Protein 2Cell biologyEndotoxins010602 entomologyCyclic nucleotide-binding domainSf21 cellstruncated transporterInsect ProteinsHeterologous expressionMultidrug Resistance-Associated ProteinsToxins
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Seasonal survival in a non-hibernating Mediterranean garden dormouse population

2020

The seasonal survival pattern of a garden dormouse Eliomys quercinus population was studied in a Mediterranean agricultural field area from East Spain, a geographical location in which this species does exhibit no hibernation. Individuals were captured from nest—boxes checked monthly during a 4-year period. Data were analysed using an open population Cormack–Jolly–Seber model including sex, age class and season as factors. Best models included the effect of age and differences in survival between adult males and females. Survival rate was more variable between seasons in males than in females or juveniles. Maximum adult male survival was reached in autumn, decreased in winter and dropped to…

0106 biological sciencesHibernationMediterranean climateSurvivalPopulationZoologyMediterranean010603 evolutionary biology01 natural sciencesbiology.animalAgricultural landEliomys0501 psychology and cognitive sciences050102 behavioral science & comparative psychologyDormouseeducationSurvival rateEcology Evolution Behavior and Systematicseducation.field_of_studyGarden dormousebiologyAgricultural land; Dormouse; Eliomys; Mediterranean; Survival05 social sciencesEcologíabiology.organism_classificationAnimal ecologyDormouseEliomysAnimal Science and Zoology
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Survival cost of an early immune soliciting in nature.

2009

8 pages; International audience; If immune functions confer obvious benefits to hosts, life-history theory assumes that they also induce costs, leading to trade-offs between immunity and other fitness components. However, whether substantial fitness costs are associated with immune systems in the wild is debatable, as numerous factors may influence the costs and benefits associated with immune activation. Here, we explore the survival cost of immune deployment in postfledging birds. We injected Eurasian collared dove nestlings (Streptopelia decaocto) with antigens from Escherichia coli, and examined whether this immune challenge affected survival after fledging. To assess survival, birds we…

0106 biological sciencesMESH : Escherichia coliimmune defensesMESH : Bird Diseases[ SDV.IMM.IA ] Life Sciences [q-bio]/Immunology/Adaptive immunology01 natural sciencesMESH: Bird DiseasesPredationNesting BehaviorBody SizeMESH: AnimalsMESH: Nesting BehaviorEscherichia coli InfectionsMESH : Adaptation Physiological0303 health sciencesbiologyMESH: Escherichia coli[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]StreptopeliaFledgeMESH : Antigens BacterialMESH : Immunity InnateAdaptation Physiological[ SDV.BID.EVO ] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE][SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunologyMESH : Escherichia coli InfectionsMESH: Survival AnalysisMESH: Immunity InnateGeneral Agricultural and Biological Sciencessurvival.Immune activationfitness costMESH : Body SizeMESH : Nesting Behavior010603 evolutionary biologysurvivalBirds03 medical and health sciencesImmune systemAntigenImmunityGeneticsEscherichia coliAnimalsColumbidaeEcology Evolution Behavior and SystematicsMESH: Escherichia coli Infections030304 developmental biologyMESH: ColumbidaeAntigens BacterialMESH: Body SizeBird Diseasesbiology.organism_classificationMESH: Adaptation PhysiologicalSurvival AnalysisImmunity Innatefree-ranging vertebrateImmunologybacteriaMESH : AnimalsMESH : Survival AnalysisMESH : ColumbidaeMESH: Antigens BacterialFitness cost
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Post-copulatory sexual selection allows females to alleviate the fitness costs incurred when mating with senescing males.

2019

8 pages; International audience; Male senescence has detrimental effects on reproductive success and offspring fitness. When females mate with multiple males during the same reproductive bout, post-copulatory sexual selection that operates either through sperm competition or cryptic female choice might allow females to skew fertilization success towards young males and as such limit the fitness costs incurred when eggs are fertilized by senescing males. Here, we experimentally tested this hypothesis. We artificially inseminated female North African houbara bustards with sperm from dyads of males of different (young and old) or similar ages (either young or old). Then, we assessed whether si…

0106 biological sciencesMaleOffspringEvolutionpaternal ageBiology010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyBirds03 medical and health sciencesReproductive senescenceSexual Behavior Animalreproductive senescenceAnimalsMatingSperm competitionLife History Traits030304 developmental biologyGeneral Environmental Science0303 health sciencesGeneral Immunology and MicrobiologyReproductive successoffspring survivalReproductionGeneral MedicineSpermSpermatozoaFemale sperm storageSexual selectionFertilizationFemalesperm selection[SDE.BE]Environmental Sciences/Biodiversity and EcologyGeneral Agricultural and Biological Sciencessiring successDemography[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Ergosterol elicits oxidative burst in tobacco cells via phospholipase A2 and protein kinase C signal pathway

2004

Ergosterol, a typical fungal sterol, induced in tobacco (Nicotiana tabacum L. cv. Xanthi) suspension cells the synthesis of reactive oxygen species and alkalization of the external medium that are dependent on the mobilization of calcium from internal stores. We used specific inhibitors to elucidate the signal pathway triggered by ergosterol compared with cryptogein, a proteinaceous elicitor of Phytophthora cryptogea. HerbimycinA and genistein, inhibitors of tyrosine protein kinases, had no effect on the oxidative burst and pH changes induced by bothelicitors.Similarly,H-89,aninhibitorofproteinkinaseA,hadnoeffectontheinductionofthesedefensereactions.However,theresponse to both elicitors was…

0106 biological sciencesTime FactorsCell SurvivalPhysiologyPlant Science01 natural sciencesPhospholipases AFungal Proteins03 medical and health scienceschemistry.chemical_compoundPhospholipase A2ErgosterolPROTEINE KINASE CTobacco[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular Biologypolycyclic compoundsGenetics[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyEnzyme InhibitorsEstrenesProtein kinase ACells CulturedProtein Kinase CProtein kinase CComputingMilieux_MISCELLANEOUS030304 developmental biologySulfonamides0303 health sciencesErgosterolbiologyPhospholipase CAlgal ProteinsNeomycinIsoquinolinesPyrrolidinonesSterolElicitorRespiratory burstOxidative StressPhospholipases A2chemistryBiochemistryType C Phospholipasesbiology.proteinlipids (amino acids peptides and proteins)Signal Transduction010606 plant biology & botany
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